I am vey critical of the brands of treats I feed my two shih-tzu. Although Twistix is made in China, I have trusted this specific brand for years now and the majority of their other treats are made in Plano, Texas. I began feeding this to my pets as a means of protecting their dental health. This is perhaps one of the only treats that contain a beneficial ingredient called sodium hexametaphosphate which is known to coat the teeth and prevent tartar from forming. My dogs have never have dental problems and always give the sweetest, freshest kisses. Give this treat as a before bed time snack so the healthy ingredients such as SH, parsley and peppermint can thoroughly clean their teeth while they sleep.