I can't really say a lot about this product because, like Denosyl, I use it as a supplement to strengthen my dog's liver, since he is being treated with phenobarbital due to epilepsy. The only issue I've had so far is that because of the size of tablet and the fact that it cannot be cut, Benji has thrown it up on a couple of ocassions. Denestra is much larger so I prefer Denosyl for Benji.