My little Chihuahua mix who is 14+ years old has been having a lot of problems over the past several months. She is deaf, can't see very well, and has weakness in both her back legs. Due to her hearing and vision losses she had been just kind of standing around much of the time, acting like she didn't know where to go or what to do. She has been on SAM-E now for about a month and I think it has helped her. She is more alert and interacts with me and our other pets more than she was before. She can also navigate her way through the house better, which is a big plus for her and for me.